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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of diabetic cataract
ncRNA name mmu-miR-211
ncRNA Category miRNA
Disease name diabetic cataract
Species Mus musculus
Tissues/Cell_line lens capsule
Methods immunohistochemistry, TUNEL assay, qRT-PCR, Western blot, transfection, luciferase reporter gene assay, MTT assay, flow cytometry, Annexin V/PI double staining
Expression pattern up-regulated
Functional description miR-211 could promote apoptosis and inhibit proliferation of lens epithelial cells in diabetic cataract mice by targetting SIRT1.
PubMed ID 28679650
Year 2017
Title Effects of microRNA-211 on proliferation and apoptosis of lens epithelial cells by targeting SIRT1 gene in diabetic cataract mice.
Drug-related ncRNA NO

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